PULLAMSETTI LAB

PhD in Molecular biology, Epigenetics, Bioinformatics (m/f/d)

Project description:

Pullamsetti´s lab is seeking a new PhD student in the area of single-cell omics in pulmonary hypertension. Your project will be a combination of single-cell multi-omics data analysis along with various functional assessments to understand the underlying pulmonary vascular and right ventricular remodeling mechanisms in pulmonary hypertension, a cardiovascular and pulmonary disease. The project aims to integrate multi-modal data ( mainly transcripts and epigenetic signals) generated from different animal models as well as human patients, to identify the driver epigenetics alterations and time-dependent dynamics of adaptive and maladaptive remodeling. This PhD project will fulfill the development of a novel (interactive) analysis workflow, as well as applying cutting-edge wet-lab techniques to validate and assess the targets, and also evaluate the clinical applications. The labs of Pullamsetti are located in Max Planck Institute for Heart and Lung Research, Bad Nauheim, and Justus Liebig University, Giessen, Germany. This PhD position is funded by a project of the Collaborative Research Center (SFB 1213). Being part of the SFB 1213 and in the networks of Cardio Pulmonary Institute (CPI) and German Lung Center (DZL), will benefit your excellent scientific collaborations.

Responsibilities

Single-cell level data analysis and interpretation
Planning, documentation, and communication of project progress and analysis of the results
Writing and contributing to scientific publicationss

Qualifications

Master or equivalent in molecular biology, computational biology, or relevant fields.
Willingness to learn new techniques and skills as projects require
Experience in analysis of next-generation sequencing (NGS) data
Scientific curiosity beyond bioinformatics development toward cardiovascular disease and clinical applications
Good communication, interpersonal and English language skills
Knowledge in single-cell omics data generation and analysis is a strong plus
Proficient in programming and data analysis in Python or R will be advantageous.
Excellent English language skills (both written and spoken)

What we offer you

International work environment
outstanding research infrastructure
Work-life balance
Support for attending international training courses and conferences
Discounted public transport state ticket

We support and promote equal opportunities and diversity in its employment relations. The salary is in accordance with the collective labour agreement of the State of Hessen (E 13, 65% TV-H).

Interested candidates should submit their electronic application by 15.09.2022 (CV, publication list, and references, max. 10 pages, one pdf) to Soni Pullamsetti (Email: Soni.Pullamsetti@mpi-bn.mpg.de)